ZEISS CLARUS 500 Fundus Camera
Warsaw · Krakow · Vienna · Zurich
The ZEISS CLARUS 500 is the latest ultra-widefield retinal camera, a fundus camera that captures color images of the fundus. The colors correspond to the natural coloration of the fundus, which significantly simplifies diagnosis and facilitates the documentation of eye disease progression, thereby providing unprecedented safety during the diagnosis of the optic nerve, as well as nevi and lesions within the eye.
ZEISS CLARUS 500 – Accurate Fundus Images
The ZEISS CLARUS 500 is the latest ultra-widefield retinal camera, a fundus camera that captures color images of the fundus. The colors correspond to the natural coloration of the fundus, which significantly simplifies diagnosis and facilitates the documentation of eye disease progression, thereby providing unprecedented safety during the diagnosis of the optic nerve, as well as nevi and lesions within the eye. ZEISS CLARUS generates images that closely resemble the fundus coloration visible during clinical examination. Images are captured in high resolution within a very wide field of view (up to 200°). Due to the wide scan size, the ZEISS CLARUS 500 can reveal changes in the eye that are difficult to visualize with a digital camera or traditional color photography. Widespread or bilateral retinal changes can alter not only the prognosis and diagnosis but also the treatment of patients.
Diagnosis of Peripheral Retinal Changes
With the introduction of ultra-widefield, high-resolution imaging (up to 7 micrometers) into retinal diagnostics, it has been established that disease symptoms can often be observed in its outermost periphery. This is the case, for example, in diabetic retinopathy. Recent studies on the use of ultra-widefield imaging in diabetic retinopathy have shown that 51% of all patients had changes that were predominantly peripheral. The presence of peripheral diabetic retinopathy is associated with a 4.7-fold increased risk of progression to PDR and a 3.2-fold increased risk of progression in diabetes by at least 2 levels.
The ZEISS CLARUS 500 captures detailed and precise retinal images, from the macula to the periphery. This allows for the detection of subtle signs of disease that are difficult to see directly or in low-resolution fundus photographs.
More Accurate Images, Better Diagnosis
For conventional ultra-widefield imaging systems, a classic high-resolution fundus camera is essential for the diagnosis and treatment of optic nerve and macular diseases. The ZEISS CLARUS 500 is the first and only fundus imaging system that allows for faithful reproduction of colors and details across a very wide field of view. This enables physicians to capture high-resolution images of the macular fundus from the macula to its periphery.
The ZEISS CLARUS 500 enables physicians to detect even the smallest changes in the course of a disease. In addition to true-color fundus images, the system also captures high-resolution fundus autofluorescence (FAF) images in blue and green, as well as infrared (IR) and external images. The very high resolution of the CLARUS 500, combined with intuitive testing software, allows physicians to reliably track changes.

CLARUS 500 – Accurate Assessment of Retinal Changes
In addition to the aforementioned diabetic retinopathy, the ZEISS CLARUS 500 helps detect and document the size and pigmentation of choroidal nevi. Images captured with the CLARUS 500 can be separated into red, green, and blue channel images, which can improve the visual contrast of details in certain retinal layers. True-color imaging is also ideal for detecting abnormalities occurring over choroidal nevi, such as yellow drusen and orange lipofuscin. Yellow drusen are most often a sign of a benign change, while the presence of orange lipofuscin usually indicates a suspicious lesion requiring further evaluation. Using different color channels can help differentiate choroidal lesions that are better visualized with red light from more superficial lesions, such as CHRPE, which are better imaged with green light. By using serial fundus photography, any significant changes in size and pigmentation can be easily assessed. These changes may indicate choroidal melanoma and require further evaluation. Infrared imaging and FAF can help visualize dysfunction of lipofuscin or the retinal pigment epithelium (RPE), which may suggest a metabolically active lesion, such as a small choroidal melanoma.
Modern Eye Examination Without Discomfort
Due to its wide range of technical features and ease of use, the ZEISS CLARUS 500 can be the sole fundus camera in any practice, whether it’s a high-volume multi-specialty clinic or a single-physician office.
Simple, stable, and intuitive, the ZEISS CLARUS 500 is an ultra-widefield retinal camera specifically designed to optimize every patient’s experience. This ultra-modern fundus camera allows images to be taken in such a way that no shadows related to eyelashes or eyelids appearing in the lens’s field of view are visible in the photograph. Live infrared retinal preview helps the operator obtain sharp images without the need for multiple shots. It also allows the operator to optimize alignment, while ensuring that eyelids and eyelashes do not interfere with image capture, which reduces examination time and eliminates patient exposure to excessive flashes. The head and chin rest enable proper camera positioning. The ZEISS CLARUS 500 uses a standard slit lamp/joystick and chin rest to improve patient comfort and relieve patient strain during the examination.
Easy Operation and Quick Analysis of Results
The ability to rotate the device between the right and left eye allows the operator to capture high-quality images without needing to reposition the patient.
The ZEISS CLARUS 500 combines an easy image acquisition platform with an intuitive user interface, enabling seamless image review. Sequential imaging of pathological changes is simplified by dragging forward annotations from the previous image. The evaluation of multiple images simultaneously, including different color channels and FAF, is streamlined by coordinating images to the same retinal location and magnification.